.357 SIGThere is almost nothing this one can't do. I wrote about the .357 Sig in large detail in the past, if you need a good read, check it out. Basically, the .357 Sig takes all of the positives from the .40, the 9mm and the .357 Magnum and combines it into one crazy self-defense cartridge.
Unbeknownst to me, this round hasn't picked up much steam in the gun world. You'd think that, based on what it is capable of, it would be a top seller. But, it isn't and it is slightly more expensive than some of the others on this list. Still, this is an excellent stopper, trusted by many law enforcement agencies.